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Organic pollution has been on the rise in the Danube over the last century, as human activities have resulted in increasing loads of wastewater rich in organic matter. The most serious organic pollution problems occur in tributaries that regularly receive untreated or inadequately treated wastewater from industrial plants and municipalities. Thanks to the significant improvement of wastewater infrastructure and services in the Danube countries, the basin-wide organic emissions reduced by 60% since the mid 2000s.

The Black Sea Commission is an intergovernmental organisation responsible for the implementation of the Convention on the Protection of the Black Sea against Pollution, and sets the legal framework required for regional cooperation and the activities necessary to reduce pollution and enhance the protection of the marine environment.