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Evidence on plastic pollution has already been gathered in both the freshwater systems and the marine environment (including the Danube and the Black Sea) over the last decades. Scientific investigations identified strong linkages between marine pollution, terrestrial areas and land-based activities. Poor waste management, everyday littering, plastic industry facilities, consuming of products of textile and cosmetic industries in households and tire abrasion pollute rivers that further discharge plastic litter into the receiving seas. While priority should be given to reducing plastic pollution at source, river clean-up actions are also highly important to eliminate plastic litter accumulation hot-spots.

North Macedonia, officially the Republic of North Macedonia, is a landlocked country in Southeast Europe. Its terrain is mostly rugged, located between the Šar Mountains and Osogovo, which frame the valley of the Vardar River. Three large lakes - Lake Ohrid, Lake Prespa, and Dojran Lake - lie on the southern borders, bisected by the frontiers with Albania and Greece. Ohrid is considered one of the world's oldest lakes and biotopes.