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The Sava River is the largest tributary in discharge and the second largest in catchment area. The International Sava River Basin Commission was established in 2005 to implement the Framework Agreement on the Sava River Basin (FAS RB.) The commission’s main goal is coordinating transboundary cooperation in the Sava River Basin.

Hazardous substances can remain in the environment for a very long time, and harm ecosystems and human health. Although monitoring indicates that the loads of some substances have been reduced in recent years, many problems still persist. The increasing number of these man-made substances present in the environment is a matter of concern, and calls for the application of the precautionary principle.

The Sava is the Danube's largest tributary of the Danube in terms of discharge and the second largest in terms of catchment area. The Sava is shared by Slovenia, Croatia, Bosnia and Herzegovina, Serbia and Montenegro. The joint management arrangements acted as a pilot for the implementation of the European Union's Water Framework Directive for the Danube and Europe.