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Evidence on plastic pollution has already been gathered in both the freshwater systems and the marine environment (including the Danube and the Black Sea) over the last decades. Scientific investigations identified strong linkages between marine pollution, terrestrial areas and land-based activities. Poor waste management, everyday littering, plastic industry facilities, consuming of products of textile and cosmetic industries in households and tire abrasion pollute rivers that further discharge plastic litter into the receiving seas. While priority should be given to reducing plastic pollution at source, river clean-up actions are also highly important to eliminate plastic litter accumulation hot-spots.

Moldova is one of the smaller countries of the Danube River Basin, but the Danube touches the southern point of Moldova for about 340 meters. Picturesque Moldova holds over 12,500km² of the Danube River Basin, including 8,300km² of the Prut River Sub-Basin, 3,300km² of the Yalpugh River Sub-Basin and 900km² of the Cahul River Sub-Basin.

As both the largest remaining natural wetland and second largest river delta in Europe, the Danube Delta is one of the continent's most valuable habitats for wetland wildlife. Pollution and discharge manipulation from upstream has a huge effect on this area of high biodiversity, plus the delta continues to change ecologically itself – the Danube Delta spreads seaward at a rate of 10 to 25 metres every year.