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The Danube River Basin is Europe's second largest river basin, with a total area of 801,463 km². It is the world's most international river basin, flowing through the territory of 19 countries. The ecosystems of the Danube River Basin are highly valuable in environmental, economic, historical and social terms, but they are subject to increasing pressure and serious threats of pollution from agriculture, industry and cities.

The Black Sea Commission is an intergovernmental organisation responsible for the implementation of the Convention on the Protection of the Black Sea against Pollution, and sets the legal framework required for regional cooperation and the activities necessary to reduce pollution and enhance the protection of the marine environment.